Bio Sketch

Jessica Damoiseaux, Ph.D., is an Associate Professor in the Institute of Gerontology and the Department of Psychology, and Director of the Ben L. Silberstein Institute for Brain Health. Dr. Damoiseaux' main research goal is to understand the changes in cognitive and brain health that either accompany typical aging or may indicate early neurodegenerative disease. She is particularly interested in identifying individual risk factors for neurodegenerative disease and examining the potential of lifestyle interventions to maintain, or improve, cognitive and brain health in older adults.

Dr. Damoiseaux uses multiple magnetic resonance imaging (MRI) approaches to study brain health, with a focus on large-scale brain network function, white matter integrity and structural brain volumetrics.

Education

PhD in Cognitive Neuroscience (2008)
VU University Medical Center, Amsterdam, the Netherlands.

M.Sc. in Psychology (2003)
Utrecht University, Utrecht, the Netherlands

Research Focus

 Dr. Damoiseaux's research aims to identify older adults at risk for neurodegenerative disease and early detection of atypical cognitive and brain function. Areas of interest include: older adults' subjective perception of cognitive decline, blood-based biomarkers, early environmental influences, genetics etc. 

In addition, Dr. Damoiseaux is interested in the potential of lifestyle interventions to maintain, or improve, cognitive and brain health in older adults. She currently collaborates with Dr. Neha Gothe from NorthEastern University on a randomized controlled trial examining the effects of yoga, aerobic and stretching exercise on neurocognitive performance in older adults.

 

Office Location

http://connectlab.wayne.edu/

Areas of Expertise

Neuroimaging, Cognition, Resting State fMRI, Functional Connectivity, Aging, Neurodegenerative Disease. 

Training

Postdoctoral research fellow, April 2008 - March 2013
Stanford School of Medicine, Stanford, CA
Department of Neurology and Neurological sciences
Functional Imaging in Neuropsychiatric Disorders (FIND) Laboratory

Studied brain network plasticity and the effect of genes on brain function in healthy aging, neurological and psychiatric patient populations. PI: Michael Greicius MD.
 

Publications

List of publications on Google Scholar 

Selected publications:

• Adriana L Ruiz-Rizzo, Kathrin Finke, Jessica S Damoiseaux,… DELCODE study group (2024). Fornix fractional anisotropy mediates the association between Mediterranean diet adherence and memory four years later in older adults without dementia. Neurobiology of Aging.
• Jung, Y., & Damoiseaux, J. S. (2024). The potential of blood neurofilament light as a marker of neurodegeneration for Alzheimer’s disease. Brain 147 (1), 12-25.
• Gothe, N. P., Erlenbach, E., Garcia, V., Malani, R., Voss, S., Camacho, P. B., McAuley, E., Burd, N., Sutton, B. P., & Damoiseaux, J. S. (2023). Yoga, aerobic and stretching exercise effects on neurocognition: Randomized controlled trial protocol. Contemporary Clinical Trials, 131, 107240.
• Uddin, L. Q., Betzel, R. F., Cohen, J. R., Damoiseaux, J. S., Brigard, F. D., Eickhoff, S. B., Fornito, A., Gratton, C., Gordon, E. M., Laird, A. R., Larson-Prior, L., McIntosh, A. R., Nickerson, L. D., Pessoa, L., Pinho, A. L., Poldrack, R. A., Razi, A., Sadaghiani, S., Shine, J. M., … Spreng, R. N. (2023). Controversies and progress on standardization of large-scale brain network nomenclature. Network Neuroscience.
• Ruiz-Rizzo, A. L., Viviano, R. P., Daugherty, A. M., Finke, K., Müller, H. J., & Damoiseaux, J. S. (2022). Subjective cognitive decline predicts lower cingulo-opercular network functional connectivity in individuals with lower neurite density in the forceps minor. NeuroImage, 263, 119662
• Hebling Vieira, B, Liem, F, Dadi, D, Engemann, DA, Gramfort, A, Bellec, P, Craddock, RC, Damoiseaux, JS, Steele, CJ, Yarkoni, T, Langer, N, Margulies, DS, Varoquaux, G. (2022). Predicting future cognitive decline from non-brain and multimodal brain imaging data in healthy and pathological aging. Neurobiology of Aging 118, 55-65.
• Boots, A., Thomason, M. E., Espinoza-Heredia, C., Pruitt, P. J., Damoiseaux, J. S., Roseboom, T. J., & de Rooij, S. R. (2022). Sex-specific effects of prenatal undernutrition on resting-state functional connectivity in the human brain at age 68. Neurobiology of Aging, 112, 129–138.
• Viviano, R. P., & Damoiseaux, J. S. (2021). Longitudinal change in hippocampal and dorsal anterior insulae functional connectivity in subjective cognitive decline. Alzheimer’s Research & Therapy, 13(1), 108.
• Zhang, J., Kucyi, A., Raya, J., Nielsen, A. N., Nomi, J. S., Damoiseaux, J. S., Greene, D. J., Horovitz, S. G., Uddin, L. Q., & Whitfield-Gabrieli, S. (2021). What have we really learned from functional connectivity in clinical populations? NeuroImage, 242, 118466.
• Ruiz-Rizzo, A., Pruitt, P., Finke, K., Müller, H., & Damoiseaux, J. (2021). Lower-Resolution Retrieval of Scenes in Older Adults With Subjective Cognitive Decline. Archives of Clinical Neuropsychology.
• Jung, Y., Viviano, R. P., van Rooden, S., van der Grond, J., Rombouts, S. A. R. B., & Damoiseaux, J. S. (2021). White Matter Hyperintensities and Apolipoprotein E Affect the Association Between Mean Arterial Pressure and Objective and Subjective Cognitive Functioning in Older Adults. Journal of Alzheimer’s Disease, 84(3), 1337–1350.
• Viviano RP, Damoiseaux JS (2020). Functional Neuroimaging in Subjective Cognitive Decline: Current Status and a Research Path Forward. Alzheimer's Research & Therapy 12 (1), 1-18.
• Gothe NP, Kahn I, Hayes JM, Erlenbach E, Damoiseaux JS, 2019. Yoga Effects on Brain Health: A Systematic Review of the Current Literature. Brain Plasticity 5, 105-122.
• Viviano RP, Hayes JM, Pruitt PJ, Fernandez Z, van Rooden S, van der Grond J, Rombouts SA, Damoiseaux JS, 2019. Aberrant memory system connectivity and working memory performance in subjective cognitive decline. NeuroImage185, 556-564.
• van Rooden S, van den Berg-Huysmans AA, Croll PH, Labadie G, Hayes JM, Viviano RP, van der Grond J, Rombouts SA, Damoiseaux JS, 2018. Subjective cognitive decline is associated with greater white matter hyperintensity volume. J Alzheimers Dis. 1-12.
• Damoiseaux JS, Viviano RP, Yuan P, Raz N, 2016. Differential Effect of Age on Posterior and Anterior Hippocampal Functional Connectivity. NeuroImage 133, 468–476.
• Damoiseaux JS, Prater K, Miller BL, Greicius MD, 2012. Functional connectivity tracks clinical deterioration in Alzheimer's disease. Neurobiol Aging Apr;33(4):828.e19-30.
• Damoiseaux JS, Beckmann CF, Sanz-Arigita EJ, Barkhof F, Scheltens P, Stam CJ, Smith SM, Rombouts SA, 2008. Reduced resting-state brain activity in the "default network" in normal aging. Cereb Cortex Aug;18(8):1856-64.
• Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, Beckmann CF, 2006. Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci U S A. Sep 12;103(37):13848-53.
 

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