Research Labs

Cognitive Neuroscience of Aging Lab

Principle Investigator: Naftali Raz, PhD
Phone: 313-664-2618
Research in this lab explores how the brain changes with age and how these changes are related to changes in memory and problem solving skills in healthy adults. We are especially interested in finding out how individual differences in predisposition to vascular disease affect age-related changes in brain and cognition. Since 2001, we have been conducting a long-term follow-up longitudinal investigation, in which we use magnetic resonance imaging (MRI) to study changes in brain structure in healthy adult volunteers within a wide age range (18 – 90 years). We also conduct studies on age-related differences in various cognitive abilities such as memory, problem solving, and spatial navigation.

The Daugherty Lab: Healthy Brain Aging

Principle Investigator: Ana Daughtery, PhD
Phone: 313-577-3403

In the Healthy Brain Aging Lab, we study metabolic and vascular health factors that shape neural and cognitive changes across the lifespan. We use advanced noninvasive neuroimaging techniques, cognitive assessments, physiological markers, and genetics to evaluate individual differences in the course of aging, including both risk (e.g., metabolic syndrome) and protective (e.g., aerobic exercise) health factors.


IOG Principle Investigator: Vojko Kavcic, PhD
Early and accurate detection of cognitive problems in older adults is a valuable weapon in the fight against Alzheimer's and other dementias. Vojko Kavcic,  PhD, is conducting a large-scale evaluation of a safe, noninvasive, low-cost, portable method to test older African Americans for brain changes that may presage Alzheimer's. He partners with Dr. Bruno Giordani of the University of Michigan on the project. This research is supported by the National Institutes of Health.

ConnectLab: Brain Connectivity and Aging

Principle Investigator: Jessica S. Damoiseaux
Phone: (313)-664-2668
This Lab seeks to elucidate how brain morphology and function change over time in healthy older adults with and without memory complaints. Changes in functional brain connectivity and brain structure are measured with resting state functional magnetic resonance imaging (RS-fMRI), diffusion weighted imaging (DWI), and structural magnetic resonance imaging (MRI). The lab aims to detect possible early biomarkers for Alzheimer's disease (AD) and other dementias.

Ofen Lab: Cognitive and Brain Development Lab

Principle Investigator: Noa Ofen, PhD
313-664-2644, 2645 or 2646
Research focused on how children and adults learn and remember information. We are particularly interested in understanding the brain basis for learning and memory, and how changes in the brain as children mature into adulthood are linked to changes in behavior.